BDBM50160870 CHEMBL3787344::US11896597, Compound EGF816::WO2022090481, Example nazartinib
SMILES CN(C)C\C=C\C(=O)N1CCCC[C@H](C1)n1c(NC(=O)c2ccnc(C)c2)nc2cccc(Cl)c12
InChI Key InChIKey=IOMMMLWIABWRKL-WUTDNEBXSA-N
Data 23 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50160870
TargetEpidermal growth factor receptor [1-18,20-1210,T790M](Homo sapiens (Human))
Boehringer Ingelheim International
WIPO
Boehringer Ingelheim International
WIPO
Affinity DataIC50: 4.10nMAssay Description: This assay quantifies the phosphorylation of EGFR at Tyr1068 and was used to measure the inhibitory effect of compounds on the transgenic EGFR del19...More data for this Ligand-Target Pair